Construct · 1 fields · 1 citations

nucleation-dependent polymerization: a standalone construct

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nucleation-dependentpolymerization1 CONSTRUCTNucleation-dependentJARRETT · STRUCTURAL BIOLOGY

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Structural biology

the model that amyloid fibrils form only after a slow, unfavorable nucleus appears, after which preformed seeds rapidly recruit further protein.

In structural biology, nucleation-dependent polymerization refers to the model that amyloid fibrils form only after a slow, unfavorable nucleus appears, after which preformed seeds rapidly recruit further protein. This meaning comes from Jarrett (1993) in Cell.[1]

Unit
Recovery means
Measured by

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Nearby constructs

amyloid seeding1 fields · 1 citationsanchor · a standalone constructcell2 fields · 3 citationsjingle · one word, two constructsform4 fields · 7 citationsjingle · one word, four constructs

References

  1. Jarrett, J. T., & Lansbury, P. T. (1993). Seeding “one-dimensional crystallization” of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie? Cell, 73(6), 1055-1058. https://doi.org/10.1016/0092-8674(93)90635-4

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