Where does origin collide?

In mathematics the origin is the fixed point from which all positions in a coordinate system are measured: the point where the axes cross and every coordinate is zero, written (0, 0) in the plane or (0, 0, 0) in space. Descartes's La Géométrie founded the practice of pinning geometry to such a reference point and reading off position as distance along perpendicular directions. The referent is a chosen zero point that anchors measurement and relative to which vectors, distances, and transformations are defined; it is an abstract location in a coordinate frame, not a stretch of DNA or an attachment on a bone.[1]

Unit

A reference point with all coordinates equal to zero

Recovery means

Not applicable

Measured by

Fixed by choice of coordinate frame; positions are then measured as signed distances from it along each axis

In molecular biology the origin (origin of replication, or ori) is the specific DNA sequence at which the machinery that copies the genome is first assembled and strand separation begins, so that replication spreads outward from it along the chromosome. Jacob, Brenner, and Cuzin's 1963 On the regulation of DNA replication in bacteria proposed the replicon model, in which an origin paired with an initiator protein defines a unit of replication and governs when copying starts. The referent is a discrete, recognisable locus on a nucleic acid that licenses and launches genome duplication, unrelated to a coordinate zero point or a muscle's bony attachment beyond the shared meaning of a place where something starts.[2]

Unit

A defined DNA locus at which replication initiates

Recovery means

Not applicable

Measured by

Mapped by marker-frequency gradients, autonomously replicating-sequence assays, and sequencing of initiation sites