Construct · 1 fields · 1 citations

orthogonal protection: a standalone construct

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orthogonalprotection1 CONSTRUCTOrthogonal protectionBARANY · ORGANIC CHEMISTRY

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Organic chemistry

using sets of protecting groups that are each removed by different conditions, so one can be taken off without disturbing the others.

In organic chemistry, orthogonal protection refers to using sets of protecting groups that are each removed by different conditions, so one can be taken off without disturbing the others. This meaning comes from Barany (1977) in Journal of the American Chemical Society.[1]

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References

  1. Barany, G., & Merrifield, R. B. (1977). A new amino protecting group removable by reduction. Chemistry of the dithiasuccinoyl (Dts) function. Journal of the American Chemical Society, 99(22), 7363-7365. https://doi.org/10.1021/ja00464a050

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