Construct · 1 fields · 1 citations

p-i concept: a standalone construct

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Toxicology

proposal that some drugs trigger hypersensitivity by binding directly and noncovalently to immune receptors, without forming haptens.

In toxicology, p-i concept refers to proposal that some drugs trigger hypersensitivity by binding directly and noncovalently to immune receptors, without forming haptens. This meaning comes from Pichler (2002) in Current Opinion in Allergy and Clinical Immunology.[1]

Unit
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Nearby constructs

binding4 fields · 4 citationsjingle · one word, four constructs current3 fields · 6 citationsjingle · one word, three constructs trigger3 fields · 5 citationsjingle · one word, three constructs

References

Pichler, W. J. (2002). Pharmacological interaction of drugs with antigen-specific immune receptors: the p-i concept. Current Opinion in Allergy and Clinical Immunology, 2(4), 301-305. https://doi.org/10.1097/00130832-200208000-00003

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