Construct · 1 fields · 1 citations

PEGylation: a standalone construct

One name. One construct. A landmark on the map.

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PEGylation1 CONSTRUCTPEGylationABUCHOWSKI · BIOMEDICAL

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Biomedical engineering

attaching polyethylene glycol chains to a protein or drug to reduce immune recognition and lengthen circulation time.

In biomedical engineering, PEGylation refers to attaching polyethylene glycol chains to a protein or drug to reduce immune recognition and lengthen circulation time. This meaning comes from Abuchowski (1977) in Journal of Biological Chemistry.[1]

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Nearby constructs

circulation4 fields · 4 citationsjingle · one word, four constructsrecognition4 fields · 5 citationsjingle · one word, four constructs

References

  1. Abuchowski, A., van Es, T., Palczuk, N. C., & Davis, F. F. (1977). Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol. Journal of Biological Chemistry, 252(11), 3578-3581. https://doi.org/10.1016/s0021-9258(17)40291-2

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