Construct · 1 fields · 1 citations

phosphoramidite chemistry: a standalone construct

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phosphoramiditechemistry1 CONSTRUCTPhosphoramiditeBEAUCAGE · ORGANIC CHEMISTRY

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Organic chemistry

building DNA or RNA chains one nucleotide at a time using nucleoside phosphoramidites as reactive coupling units.

In organic chemistry, phosphoramidite chemistry refers to building DNA or RNA chains one nucleotide at a time using nucleoside phosphoramidites as reactive coupling units. This meaning comes from Beaucage (1981) in Tetrahedron Letters.[1]

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Nearby constructs

coupling4 fields · 4 citationsjingle · one word, four constructs

References

  1. Beaucage, S. L., & Caruthers, M. H. (1981). Deoxynucleoside phosphoramidites: A new class of key intermediates for deoxypolynucleotide synthesis. Tetrahedron Letters, 22(20), 1859-1862. https://doi.org/10.1016/s0040-4039(01)90461-7

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