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post-transfusion purpura: a standalone construct

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post-transfusionpurpura1 CONSTRUCTPost-transfusion purpuraSHULMAN · TRANSFUSION MEDICINE

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Transfusion medicine

sudden severe thrombocytopenia about a week after transfusion, caused by alloantibody against a platelet antigen the recipient lacks.

In transfusion medicine, post-transfusion purpura refers to sudden severe thrombocytopenia about a week after transfusion, caused by alloantibody against a platelet antigen the recipient lacks. This meaning comes from Shulman (1961) in Journal of Clinical Investigation.[1]

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References

  1. Shulman, N. R., Aster, R. H., Leitner, A., & Hiller, M. C. (1961). Immunoreactions Involving Platelets. V. Post-transfusion Purpura Due to a Complement-fixing Antibody Against a Genetically Controlled Platelet Antigen. a Proposed Mechanism for Thrombocytopenia and Its Relevance in “autoimmunity”. Journal of Clinical Investigation, 40(9), 1597-1620. https://doi.org/10.1172/jci104383

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