Construct · 1 fields · 1 citations

principal components correction for stratification: a standalone construct

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Statistical genetics

adjusting genotypes and phenotypes along the top principal components of genome-wide data to remove associations caused by ancestry differences.

In statistical genetics, principal components correction for stratification refers to adjusting genotypes and phenotypes along the top principal components of genome-wide data to remove associations caused by ancestry differences. This meaning comes from Price (2006) in Nature Genetics.[1]

Unit
Recovery means
Measured by

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Nearby constructs

principal3 fields · 6 citationsjingle · one word, three constructs stratification5 fields · 5 citationsjingle · one word, five constructs

References

Price, A. L., Patterson, N. J., Plenge, R. M., Weinblatt, M. E., Shadick, N. A., & Reich, D. (2006). Principal components analysis corrects for stratification in genome-wide association studies. Nature Genetics, 38(8), 904-909. https://doi.org/10.1038/ng1847

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