Construct · 1 fields · 1 citations

prion-like propagation: a standalone construct

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Dementia research

the idea that misfolded proteins such as amyloid beta, tau and alpha-synuclein seed further misfolding and spread between connected cells, much as prions do.

In dementia research, prion-like propagation refers to the idea that misfolded proteins such as amyloid beta, tau and alpha-synuclein seed further misfolding and spread between connected cells, much as prions do. This meaning comes from Jucker (2013) in Nature.[1]

Unit
Recovery means
Measured by

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Nearby constructs

beta3 fields · 3 citationsjingle · one word, three constructs propagation2 fields · 2 citationsjingle · one word, two constructs seed1 fields · 1 citationsanchor · a standalone construct

References

Jucker, M., & Walker, L. C. (2013). Self-propagation of pathogenic protein aggregates in neurodegenerative diseases. Nature, 501(7465), 45-51. https://doi.org/10.1038/nature12481

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