Construct · 1 fields · 1 citations

protein interface hot spot: a standalone construct

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Structural biology

a small set of interface residues that contribute most of the binding energy, typically shielded from water by a ring of less important residues.

In structural biology, protein interface hot spot refers to a small set of interface residues that contribute most of the binding energy, typically shielded from water by a ring of less important residues. This meaning comes from Bogan (1998) in Journal of Molecular Biology.[1]

Unit
Recovery means
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Nearby constructs

binding4 fields · 4 citationsjingle · one word, four constructs energy5 fields · 10 citationsjingle · one word, five constructs interface2 fields · 2 citationsjingle · one word, two constructs

References

Bogan, A. A., & Thorn, K. S. (1998). Anatomy of hot spots in protein interfaces. Journal of Molecular Biology, 280(1), 1-9. https://doi.org/10.1006/jmbi.1998.1843

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