Construct · 1 fields · 1 citations

proximity ligation assay: a standalone construct

One name. One construct. A landmark on the map.

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Cell biology

detecting that two proteins are close by joining antibody-linked oligonucleotides and amplifying the joined product.

In cell biology, proximity ligation assay refers to detecting that two proteins are close by joining antibody-linked oligonucleotides and amplifying the joined product. This meaning comes from Söderberg (2006) in Nature Methods.[1]

Unit
Recovery means
Measured by

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Nearby constructs

assay1 fields · 1 citationsanchor · a standalone construct cell2 fields · 3 citationsjingle · one word, two constructs ligation2 fields · 2 citationsjingle · one word, two constructs

References

Söderberg, O., Gullberg, M., Jarvius, M., Ridderstråle, K., Leuchowius, K., Jarvius, J., Wester, K., Hydbring, P., Bahram, F., Larsson, L., & Landegren, U. (2006). Direct observation of individual endogenous protein complexes in situ by proximity ligation. Nature Methods, 3(12), 995-1000. https://doi.org/10.1038/nmeth947

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