Construct · 1 fields · 1 citations

rosette: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed
rosette1 CONSTRUCTE-rosetteBENTWICH · E-ROSETTE

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Immunology

Red cells cluster around a lymphocyte like petals

In immunology, a rosette is the flower-like cluster that forms in vitro when indicator red blood cells bind around the surface of a single lymphocyte, so that the central cell is ringed by adherent cells. Bentwich, Douglas, Siegal, and Kunkel's 1973 Human lymphocyte–sheep erythrocyte rosette formation characterised the sheep-erythrocyte (E-) rosette, which became the classic marker for human T lymphocytes. The referent is a cell-binding assay read as a rosette, scored by the fraction of central cells that form one, and it is unrelated to a ring of leaves or a tumour's cell arrangement beyond the shared floral image.[1]

Unit
The proportion of central cells that bind a surrounding ring of indicator cells
Recovery means
Not applicable
Measured by
Counted microscopically as the percentage of lymphocytes forming rosettes with the indicator erythrocytes

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Nearby constructs

arrangement3 fields · 6 citationsjingle · one word, three constructsassay1 fields · 1 citationsanchor · a standalone constructcell2 fields · 3 citationsjingle · one word, two constructs

References

  1. Bentwich, Z., Douglas, S. D., Siegal, F. P., & Kunkel, H. G. (1973). Human lymphocyte–sheep erythrocyte rosette formation: Some characteristics of the interaction. Clinical Immunology and Immunopathology, 1(4), 511–522. https://doi.org/10.1016/0090-1229(73)90007-x

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