Construct · 1 fields · 1 citations

secondary nucleation: a standalone construct

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Biophysics

formation of new amyloid aggregates catalyzed on the surface of existing fibrils, which makes aggregation self-amplifying.

In biophysics, secondary nucleation refers to formation of new amyloid aggregates catalyzed on the surface of existing fibrils, which makes aggregation self-amplifying. This meaning comes from Cohen (2013) in Proceedings of the National Academy of Sciences.[1]

Unit
Recovery means
Measured by

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Nearby constructs

Lauritzen-Hoffman theory1 fields · 1 citationsanchor · a standalone construct nucleation3 fields · 6 citationsinvariant · one construct, three systems surface3 fields · 3 citationsjingle · one word, three constructs

References

Cohen, S. I. A., Linse, S., Luheshi, L. M., Hellstrand, E., White, D. A., Rajah, L., Otzen, D. E., Vendruscolo, M., Dobson, C. M., & Knowles, T. P. J. (2013). Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism. Proceedings of the National Academy of Sciences, 110(24), 9758-9763. https://doi.org/10.1073/pnas.1218402110

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