Construct · 1 fields · 1 citations

self-enhanced ligand degradation: a standalone construct

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Developmental biology

a feedback in which a morphogen raises its own rate of degradation, making the gradient robust to changes in how much is produced.

In developmental biology, self-enhanced ligand degradation refers to a feedback in which a morphogen raises its own rate of degradation, making the gradient robust to changes in how much is produced. This meaning comes from Eldar (2003) in Developmental Cell.[1]

Unit
Recovery means
Measured by

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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructs degradation3 fields · 5 citationsjingle · one word, three constructs feedback4 fields · 5 citationsjingle · one word, four constructs

References

Eldar, A., Rosin, D., Shilo, B., & Barkai, N. (2003). Self-Enhanced Ligand Degradation Underlies Robustness of Morphogen Gradients. Developmental Cell, 5(4), 635-646. https://doi.org/10.1016/s1534-5807(03)00292-2

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