Construct · 1 fields · 1 citations

semi-mechanistic myelosuppression model: a standalone construct

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semi-mechanisticmyelosuppression model1 CONSTRUCTSemi-mechanisticFRIBERG · PHARMACOMETRICS

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Pharmacometrics

pharmacodynamic model of chemotherapy-induced neutropenia with proliferating cells, maturation transit compartments and feedback, whose system parameters hold across drugs.

In pharmacometrics, semi-mechanistic myelosuppression model refers to pharmacodynamic model of chemotherapy-induced neutropenia with proliferating cells, maturation transit compartments and feedback, whose system parameters hold across drugs. This meaning comes from Friberg (2002) in Journal of Clinical Oncology.[1]

Unit
Recovery means
Measured by

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Nearby constructs

feedback4 fields · 5 citationsjingle · one word, four constructsmodel3 fields · 3 citationsjingle · one word, three constructstransit compartment model1 fields · 1 citationsanchor · a standalone construct

References

  1. Friberg, L. E., Henningsson, A., Maas, H., Nguyen, L., & Karlsson, M. O. (2002). Model of Chemotherapy-Induced Myelosuppression With Parameter Consistency Across Drugs. Journal of Clinical Oncology, 20(24), 4713-4721. https://doi.org/10.1200/jco.2002.02.140

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