Construct · 1 fields · 1 citations

site-specific mechanism of metal-mediated damage: a standalone construct

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site-specific mechanismof metal-mediated damage1 CONSTRUCTSite-specific mechanismCHEVION · BIOINORGANIC

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Bioinorganic chemistry

the proposal that biological radical damage arises where redox-active metals bind to targets, so hydroxyl radicals form and react at the binding site.

In bioinorganic chemistry, site-specific mechanism of metal-mediated damage refers to the proposal that biological radical damage arises where redox-active metals bind to targets, so hydroxyl radicals form and react at the binding site. This meaning comes from Chevion (1988) in Free Radical Biology and Medicine.[1]

Unit
Recovery means
Measured by

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Nearby constructs

binding4 fields · 4 citationsjingle · one word, four constructsform4 fields · 7 citationsjingle · one word, four constructsmechanism4 fields · 4 citationsjingle · one word, four constructs

References

  1. Chevion, M. (1988). A site-specific mechanism for free radical induced biological damage: The essential role of redox-active transition metals. Free Radical Biology and Medicine, 5(1), 27-37. https://doi.org/10.1016/0891-5849(88)90059-7

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