Construct · 1 fields · 1 citations

solid-phase synthesis: a standalone construct

One name. One construct. A landmark on the map.

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solid-phasesynthesis1 CONSTRUCTSolid-phase synthesisMERRIFIELD · ORGANIC CHEMISTRY

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Organic chemistry

assembling a molecule step by step while it is attached to an insoluble resin, so excess reagents can be washed away after each step.

In organic chemistry, solid-phase synthesis refers to assembling a molecule step by step while it is attached to an insoluble resin, so excess reagents can be washed away after each step. This meaning comes from Merrifield (1963) in Journal of the American Chemical Society.[1]

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Nearby constructs

synthesis4 fields · 5 citationsjingle · one word, four constructs

References

  1. Merrifield, R. B. (1963). Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide. Journal of the American Chemical Society, 85(14), 2149-2154. https://doi.org/10.1021/ja00897a025

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