Construct · 1 fields · 1 citations

statistical fine-mapping: a standalone construct

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Genetics and genomics

methods that narrow an association signal to the variants most likely to be causal, often reporting a credible set with posterior probabilities.

In genetics and genomics, statistical fine-mapping refers to methods that narrow an association signal to the variants most likely to be causal, often reporting a credible set with posterior probabilities. This meaning comes from Schaid (2018) in Nature Reviews Genetics.[1]

Unit
Recovery means
Measured by

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Nearby constructs

association4 fields · 4 citationsjingle · one word, four constructs posterior2 fields · 2 citationsjingle · one word, two constructs signal5 fields · 5 citationsjingle · one word, five constructs

References

Schaid, D. J., Chen, W., & Larson, N. B. (2018). From genome-wide associations to candidate causal variants by statistical fine-mapping. Nature Reviews Genetics, 19(8), 491-504. https://doi.org/10.1038/s41576-018-0016-z

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