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stochastic model of stem cell proliferation: a standalone construct

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stochastic model ofstem cell proliferation1 CONSTRUCTStochastic model of stemTILL · STEM CELL BIOLOGY

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Stem cell biology

the model that a stem cell's choice between self-renewal and differentiation is random, which explains the highly variable sizes of stem cell colonies.

In stem cell biology, stochastic model of stem cell proliferation refers to the model that a stem cell's choice between self-renewal and differentiation is random, which explains the highly variable sizes of stem cell colonies. This meaning comes from Till (1964) in Proceedings of the National Academy of Sciences.[1]

Unit
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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructsdifferentiation4 fields · 4 citationsjingle · one word, four constructsmodel3 fields · 3 citationsjingle · one word, three constructs

References

  1. Till, J. E., McCulloch, E. A., & Siminovitch, L. (1964). A Stochastic Model of Stem Cell Proliferation, Based on the Growth of Spleen Colony-forming Cells. Proceedings of the National Academy of Sciences, 51(1), 29-36. https://doi.org/10.1073/pnas.51.1.29

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