Construct · 1 fields · 1 citations

strain-promoted azide-alkyne cycloaddition: a standalone construct

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strain-promotedazide-alkyne cycloaddition1 CONSTRUCTStrain-promotedAGARD · CHEMICAL BIOLOGY

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Chemical biology

cycloaddition between an azide and a ring-strained cyclooctyne that proceeds without a toxic copper catalyst, allowing labeling of biomolecules in living systems.

In chemical biology, strain-promoted azide-alkyne cycloaddition refers to cycloaddition between an azide and a ring-strained cyclooctyne that proceeds without a toxic copper catalyst, allowing labeling of biomolecules in living systems. This meaning comes from Agard (2004) in Journal of the American Chemical Society.[1]

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labeling3 fields · 5 citationsjingle · one word, three constructs

References

  1. Agard, N. J., Prescher, J. A., & Bertozzi, C. R. (2004). A Strain-Promoted [3 + 2] Azide−Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems. Journal of the American Chemical Society, 126(46), 15046-15047. https://doi.org/10.1021/ja044996f

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