Construct · 1 fields · 1 citations

summary-data-based Mendelian randomization: a standalone construct

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summary-data-basedMendelian randomization1 CONSTRUCTSummary-data-basedZHU · STATISTICAL GENETICS

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Statistical genetics

testing whether a trait association is mediated by gene expression by combining GWAS and expression QTL summary data, with a heterogeneity test for linkage.

In statistical genetics, summary-data-based Mendelian randomization refers to testing whether a trait association is mediated by gene expression by combining GWAS and expression QTL summary data, with a heterogeneity test for linkage. This meaning comes from Zhu (2016) in Nature Genetics.[1]

Unit
Recovery means
Measured by

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Nearby constructs

association4 fields · 4 citationsjingle · one word, four constructsexpression4 fields · 4 citationsjingle · one word, four constructslinkage4 fields · 6 citationsjingle · one word, four constructs

References

  1. Zhu, Z., Zhang, F., Hu, H., Bakshi, A., Robinson, M. R., Powell, J. E., Montgomery, G. W., Goddard, M. E., Wray, N. R., Visscher, P. M., & Yang, J. (2016). Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets. Nature Genetics, 48(5), 481-487. https://doi.org/10.1038/ng.3538

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