Construct · 1 fields · 1 citations

tight-binding inhibition: a standalone construct

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tight-bindinginhibition1 CONSTRUCTTight-binding inhibitionMORRISON · ENZYMOLOGY

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Enzymology

inhibition by compounds whose dissociation constant is near the enzyme concentration, so free inhibitor depletion must be modeled with a quadratic rate equation.

In enzymology, tight-binding inhibition refers to inhibition by compounds whose dissociation constant is near the enzyme concentration, so free inhibitor depletion must be modeled with a quadratic rate equation. This meaning comes from Morrison (1969) in Biochimica et Biophysica Acta (BBA) - Enzymology.[1]

Unit
Recovery means
Measured by

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Nearby constructs

concentration4 fields · 4 citationsjingle · one word, four constructsconstant2 fields · 2 citationsjingle · one word, two constructsdepletion3 fields · 4 citationsjingle · one word, three constructs

References

  1. Morrison, J. F. (1969). Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors. Biochimica et Biophysica Acta (BBA) - Enzymology, 185(2), 269-286. https://doi.org/10.1016/0005-2744(69)90420-3

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