Construct · 1 fields · 1 citations

transcriptional condensate model: a standalone construct

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transcriptionalcondensate model1 CONSTRUCTTranscriptionalHNISZ · BIOPHYSICS

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Biophysics

the model that super-enhancers drive gene expression by forming phase-separated condensates of transcription factors and coactivators.

In biophysics, transcriptional condensate model refers to the model that super-enhancers drive gene expression by forming phase-separated condensates of transcription factors and coactivators. This meaning comes from Hnisz (2017) in Cell.[1]

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cell2 fields · 3 citationsjingle · one word, two constructsdrive2 fields · 2 citationsjingle · one word, two constructsexpression4 fields · 4 citationsjingle · one word, four constructs

References

  1. Hnisz, D., Shrinivas, K., Young, R. A., Chakraborty, A. K., & Sharp, P. A. (2017). A Phase Separation Model for Transcriptional Control. Cell, 169(1), 13-23. https://doi.org/10.1016/j.cell.2017.02.007

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