Construct · 1 fields · 1 citations

two-stage clonal expansion model: a standalone construct

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two-stage clonalexpansion model1 CONSTRUCTTwo-stage clonalMOOLGAVKAR · ONCOLOGY

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Oncology

a mathematical model of carcinogenesis in which cells pass through two rate-limiting mutations with clonal growth of intermediate cells, used to fit cancer incidence data.

In oncology, two-stage clonal expansion model refers to a mathematical model of carcinogenesis in which cells pass through two rate-limiting mutations with clonal growth of intermediate cells, used to fit cancer incidence data. This meaning comes from Moolgavkar (1981) in JNCI: Journal of the National Cancer Institute.[1]

Unit
Recovery means
Measured by

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Nearby constructs

expansion4 fields · 4 citationsjingle · one word, four expansionsgrowth4 fields · 4 citationsjingle · one word, four constructsincidence4 fields · 4 citationsjingle · one word, four constructs

References

  1. Moolgavkar, S. H., & Knudson, A. G. (1981). Mutation and Cancer: A Model for Human Carcinogenesis2. JNCI: Journal of the National Cancer Institute, 66(6), 1037-1052. https://doi.org/10.1093/jnci/66.6.1037

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