Construct · 1 fields · 1 citations

two-state receptor model: a standalone construct

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Pharmacology

model in which receptors exist in equilibrium between inactive and active conformations, with agonists acting by preferentially binding and stabilizing the active state.

In pharmacology, two-state receptor model refers to model in which receptors exist in equilibrium between inactive and active conformations, with agonists acting by preferentially binding and stabilizing the active state. This meaning comes from Leff (1995) in Trends in Pharmacological Sciences.[1]

Unit
Recovery means
Measured by

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Nearby constructs

binding4 fields · 4 citationsjingle · one word, four constructs equilibrium4 fields · 4 citationsjingle · one word, four constructs model3 fields · 3 citationsjingle · one word, three constructs

References

Leff, P. (1995). The two-state model of receptor activation. Trends in Pharmacological Sciences, 16(3), 89-97. https://doi.org/10.1016/s0165-6147(00)88989-0

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