Construct · 1 fields · 1 citations

V(D)J recombination: a standalone construct

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Immunology

the cutting and joining of separate gene segments in developing lymphocytes that generates the huge diversity of antibody and T cell receptors.

In immunology, V(D)J recombination refers to the cutting and joining of separate gene segments in developing lymphocytes that generates the huge diversity of antibody and T cell receptors. This meaning comes from Hozumi (1976) in Proceedings of the National Academy of Sciences.[1]

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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructs diversity3 fields · 3 citationsjingle · one word, three constructs recombination3 fields · 3 citationsjingle · one word, three constructs

References

Hozumi, N., & Tonegawa, S. (1976). Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions. Proceedings of the National Academy of Sciences, 73(10), 3628-3632. https://doi.org/10.1073/pnas.73.10.3628

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