Construct · 1 fields · 1 citations

Veber rules: a standalone construct

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Medicinal chemistry

criteria linking good oral bioavailability in rats to ten or fewer rotatable bonds and limited polar surface area or hydrogen-bond count.

In medicinal chemistry, Veber rules refers to criteria linking good oral bioavailability in rats to ten or fewer rotatable bonds and limited polar surface area or hydrogen-bond count. This meaning comes from Veber (2002) in Journal of Medicinal Chemistry.[1]

Unit
Recovery means
Measured by

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Nearby constructs

count2 fields · 2 citationsjingle · one word, two constructs good2 fields · 5 citationsjingle · one word, two constructs surface3 fields · 3 citationsjingle · one word, three constructs

References

Veber, D. F., Johnson, S. R., Cheng, H., Smith, B. R., Ward, K. W., & Kopple, K. D. (2002). Molecular Properties That Influence the Oral Bioavailability of Drug Candidates. Journal of Medicinal Chemistry, 45(12), 2615-2623. https://doi.org/10.1021/jm020017n

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