Construct · 1 fields · 1 citations

3+3 design: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed
3+3 design1 CONSTRUCT3+3 designLE TOURNEAU · ONCOLOGY TRIALS

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Oncology trials

a rule-based dose escalation for phase I trials that treats cohorts of three patients and expands or escalates by the number of dose-limiting toxicities.

In oncology trials, 3+3 design refers to a rule-based dose escalation for phase I trials that treats cohorts of three patients and expands or escalates by the number of dose-limiting toxicities. This meaning comes from Le Tourneau (2009) in JNCI: Journal of the National Cancer Institute.[1]

Unit
Recovery means
Measured by

Next

Run it through the Collider, or take the citations with you.

See how 3+3 design sits against neighbouring constructs in the Collider, or export every reference on this page in one click.

Open in ColliderExport BibTeXReport this entry

Nearby constructs

dose3 fields · 3 citationsinvariant · one construct, three systemsnumber3 fields · 6 citationsjingle · one word, three constructsphase5 fields · 6 citationsjingle · one word, five constructs

References

  1. Le Tourneau, C., Lee, J. J., & Siu, L. L. (2009). Dose Escalation Methods in Phase I Cancer Clinical Trials. JNCI: Journal of the National Cancer Institute, 101(10), 708-720. https://doi.org/10.1093/jnci/djp079

Cited on this page?

Confirm your construct, or correct us.

If your work is cited behind one of these entries, you know better than we do whether we captured the meaning right. Confirm it, suggest an edit, or dispute it, and your name goes on the entry as an author who has checked it, linked to your ORCID.

Claim your construct