Construct · 1 fields · 1 citations

affinity ceiling: a standalone construct

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Immunology

the upper limit on antibody binding strength reachable during a response, set when antigen capture no longer distinguishes better binders.

In immunology, affinity ceiling refers to the upper limit on antibody binding strength reachable during a response, set when antigen capture no longer distinguishes better binders. This meaning comes from Foote (1995) in Proceedings of the National Academy of Sciences.[1]

Unit
Recovery means
Measured by

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Nearby constructs

affinity3 fields · 4 citationsjingle · one word, three constructs binding4 fields · 4 citationsjingle · one word, four constructs capture4 fields · 4 citationsjingle · one word, four constructs

References

Foote, J., & Eisen, H. N. (1995). Kinetic and affinity limits on antibodies produced during immune responses. Proceedings of the National Academy of Sciences, 92(5), 1254-1256. https://doi.org/10.1073/pnas.92.5.1254

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