Construct · 1 fields · 1 citations

asparagine deamidation: a standalone construct

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asparaginedeamidation1 CONSTRUCTAsparagine deamidationWAKANKAR · BIOPHARMACEUTICAL

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Biopharmaceutical development

spontaneous loss of the amide group of asparagine giving acidic variants, with rate set by neighbouring residues and pH.

In biopharmaceutical development, asparagine deamidation refers to spontaneous loss of the amide group of asparagine giving acidic variants, with rate set by neighbouring residues and pH. This meaning comes from Wakankar (2006) in Journal of Pharmaceutical Sciences.[1]

Unit
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Measured by

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Nearby constructs

development1 fields · 2 citationsanchor · a standalone constructgroup4 fields · 4 citationsjingle · one word, four constructsloss2 fields · 3 citationsjingle · one word, two constructs

References

  1. Wakankar, A. A., & Borchardt, R. T. (2006). Formulation considerations for proteins susceptible to asparagine deamidation and aspartate isomerization. Journal of Pharmaceutical Sciences, 95(11), 2321-2336. https://doi.org/10.1002/jps.20740

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