Construct · 1 fields · 1 citations

centrality-lethality rule: a standalone construct

One name. One construct. A landmark on the map.

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Network biology

the observation that highly connected proteins in an interaction network are more often essential for viability.

In network biology, centrality-lethality rule refers to the observation that highly connected proteins in an interaction network are more often essential for viability. This meaning comes from Jeong (2001) in Nature.[1]

Unit
Recovery means
Measured by

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Nearby constructs

interaction3 fields · 7 citationsjingle · one word, three constructs network4 fields · 6 citationsjingle · one word, four constructs observation2 fields · 2 citationsjingle · one word, two constructs

References

Jeong, H., Mason, S. P., Barabási, A. -., & Oltvai, Z. N. (2001). Lethality and centrality in protein networks. Nature, 411(6833), 41-42. https://doi.org/10.1038/35075138

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