Construct · 1 fields · 1 citations

chemical probe: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed
chemicalprobe1 CONSTRUCTChemical probeARROWSMITH · CHEMICAL BIOLOGY

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Chemical biology

potent, selective and well-characterized small molecule used to test the biological role of a protein, held to explicit quality criteria.

In chemical biology, chemical probe refers to potent, selective and well-characterized small molecule used to test the biological role of a protein, held to explicit quality criteria. This meaning comes from Arrowsmith (2015) in Nature Chemical Biology.[1]

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Nearby constructs

explicit1 fields · 1 citationsanchor · a standalone constructprobe3 fields · 3 citationsjingle · one word, three constructsquality6 fields · 13 citationsjingle · one name, six constructs

References

  1. Arrowsmith, C. H., Audia, J. E., Austin, C., Baell, J., Bennett, J., Blagg, J., Bountra, C., Brennan, P. E., Brown, P. J., Bunnage, M. E., Buser-Doepner, C., Campbell, R. M., Carter, A. J., Cohen, P., Copeland, R. A., Cravatt, B., Dahlin, J. L., Dhanak, D., Edwards, A. M., Frederiksen, M., Frye, S. V., Gray, N., Grimshaw, C. E., Hepworth, D., Howe, T., Huber, K. V. M., Jin, J., Knapp, S., Kotz, J. D., Kruger, R. G., Lowe, D., Mader, M. M., Marsden, B., Mueller-Fahrnow, A., Müller, S., O'Hagan, R. C., Overington, J. P., Owen, D. R., Rosenberg, S. H., Ross, R., Roth, B., Schapira, M., Schreiber, S. L., Shoichet, B., Sundström, M., Superti-Furga, G., Taunton, J., Toledo-Sherman, L., Walpole, C., Walters, M. A., Willson, T. M., Workman, P., Young, R. N., & Zuercher, W. J. (2015). The promise and peril of chemical probes. Nature Chemical Biology, 11(8), 536-541. https://doi.org/10.1038/nchembio.1867

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