Construct · 1 fields · 1 citations

class switch recombination: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed
class switchrecombination1 CONSTRUCTClass switchMURAMATSU · IMMUNOLOGY

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Immunology

the DNA rearrangement by which B cells change the constant region of their antibodies, swapping isotype while keeping antigen specificity.

In immunology, class switch recombination refers to the DNA rearrangement by which B cells change the constant region of their antibodies, swapping isotype while keeping antigen specificity. This meaning comes from Muramatsu (2000) in Cell.[1]

Unit
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Measured by

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Nearby constructs

somatic hypermutation1 fields · 1 citationsanchor · a standalone constructcell2 fields · 3 citationsjingle · one word, two constructsclass3 fields · 3 citationsjingle · one word, three constructs

References

  1. Muramatsu, M., Kinoshita, K., Fagarasan, S., Yamada, S., Shinkai, Y., & Honjo, T. (2000). Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme. Cell, 102(5), 553-563. https://doi.org/10.1016/s0092-8674(00)00078-7

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