Construct · 1 fields · 1 citations

complement C4 hypothesis of schizophrenia: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Biological psychiatry

the proposal that genetic variants raising complement component 4 expression increase schizophrenia risk by promoting excessive synaptic pruning.

In biological psychiatry, complement C4 hypothesis of schizophrenia refers to the proposal that genetic variants raising complement component 4 expression increase schizophrenia risk by promoting excessive synaptic pruning. This meaning comes from Sekar (2016) in Nature.[1]

Unit
Recovery means
Measured by

Run it through the Collider, or take the citations with you.

See how complement C4 hypothesis of schizophrenia sits against neighbouring constructs in the Collider, or export every reference on this page in one click.

Open in Collider Export BibTeX Report this entry

Nearby constructs

complement4 fields · 5 citationsjingle · one word, four constructs component3 fields · 5 citationsjingle · one word, three constructs expression4 fields · 4 citationsjingle · one word, four constructs

References

Sekar, A., Bialas, A. R., de Rivera, H., Davis, A., Hammond, T. R., Kamitaki, N., Tooley, K., Presumey, J., Baum, M., Van Doren, V., Genovese, G., Rose, S. A., Handsaker, R. E., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Daly, M. J., Carroll, M. C., Stevens, B., & McCarroll, S. A. (2016). Schizophrenia risk from complex variation of complement component 4. Nature, 530(7589), 177-183. https://doi.org/10.1038/nature16549

Cited on this page?

Confirm your construct, or correct us.

If your work is cited behind one of these entries, you know better than we do whether we captured the meaning right. Confirm it, suggest an edit, or dispute it, and your name goes on the entry as an author who has checked it, linked to your ORCID.

Claim your construct