Construct · 1 fields · 1 citations

conformational proofreading: a standalone construct

One name. One construct. A landmark on the map.

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Biophysics

a recognition scheme in which a structural mismatch between recognizer and target improves specificity by costing binding energy.

In biophysics, conformational proofreading refers to a recognition scheme in which a structural mismatch between recognizer and target improves specificity by costing binding energy. This meaning comes from Savir (2007) in PLoS ONE.[1]

Unit
Recovery means
Measured by

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Nearby constructs

binding4 fields · 4 citationsjingle · one word, four constructs energy5 fields · 10 citationsjingle · one word, five constructs recognition4 fields · 5 citationsjingle · one word, four constructs

References

Savir, Y., & Tlusty, T. (2007). Conformational Proofreading: The Impact of Conformational Changes on the Specificity of Molecular Recognition. PLoS ONE, 2(5), e468. https://doi.org/10.1371/journal.pone.0000468

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