Construct · 1 fields · 1 citations

constitutive receptor activity: a standalone construct

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constitutivereceptor activity1 CONSTRUCTConstitutive receptorSEIFERT · PHARMACOLOGY

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Pharmacology

signaling by a receptor in the absence of any agonist, seen in wild-type and mutant receptors and reduced by inverse agonists.

In pharmacology, constitutive receptor activity refers to signaling by a receptor in the absence of any agonist, seen in wild-type and mutant receptors and reduced by inverse agonists. This meaning comes from Seifert (2002) in Naunyn-Schmiedeberg's Archives of Pharmacology.[1]

Unit
Recovery means
Measured by

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Nearby constructs

agonist1 fields · 3 citationsanchor · a standalone constructreceptor2 fields · 2 citationsjingle · one word, two constructs

References

  1. Seifert, R., & Wenzel-Seifert, K. (2002). Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors. Naunyn-Schmiedeberg's Archives of Pharmacology, 366(5), 381-416. https://doi.org/10.1007/s00210-002-0588-0

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