Construct · 1 fields · 1 citations

Cre-lox recombination: a standalone construct

One name. One construct. A landmark on the map.

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Molecular biology

using the Cre enzyme and its recognition sites to delete, invert or swap a defined DNA segment in cells.

In molecular biology, Cre-lox recombination refers to using the Cre enzyme and its recognition sites to delete, invert or swap a defined DNA segment in cells. This meaning comes from Sauer (1988) in Proceedings of the National Academy of Sciences.[1]

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Nearby constructs

recognition4 fields · 5 citationsjingle · one word, four constructs recombination3 fields · 3 citationsjingle · one word, three constructs swap1 fields · 1 citationsanchor · a standalone construct

References

Sauer, B., & Henderson, N. (1988). Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1. Proceedings of the National Academy of Sciences, 85(14), 5166-5170. https://doi.org/10.1073/pnas.85.14.5166

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