Construct · 1 fields · 1 citations

CRISPR activation: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Genome editing

raising transcription of a chosen gene by recruiting activator domains to it with an inactive Cas9.

In genome editing, CRISPR activation refers to raising transcription of a chosen gene by recruiting activator domains to it with an inactive Cas9. This meaning comes from Konermann (2014) in Nature.[1]

Unit
Recovery means
Measured by

Run it through the Collider, or take the citations with you.

See how CRISPR activation sits against neighbouring constructs in the Collider, or export every reference on this page in one click.

Open in Collider Export BibTeX Report this entry

Nearby constructs

activation4 fields · 4 citationsjingle · one word, four constructs editing1 fields · 2 citationsanchor · a standalone construct raising1 fields · 1 citationsanchor · one construct, one field

References

Konermann, S., Brigham, M. D., Trevino, A. E., Joung, J., Abudayyeh, O. O., Barcena, C., Hsu, P. D., Habib, N., Gootenberg, J. S., Nishimasu, H., Nureki, O., & Zhang, F. (2014). Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. Nature, 517(7536), 583-588. https://doi.org/10.1038/nature14136

Cited on this page?

Confirm your construct, or correct us.

If your work is cited behind one of these entries, you know better than we do whether we captured the meaning right. Confirm it, suggest an edit, or dispute it, and your name goes on the entry as an author who has checked it, linked to your ORCID.

Claim your construct