Construct · 1 fields · 1 citations

CRISPR screen: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Biotechnology

pooled perturbation of many genes with guide libraries, reading out which disruptions change a measured phenotype.

In biotechnology, CRISPR screen refers to pooled perturbation of many genes with guide libraries, reading out which disruptions change a measured phenotype. This meaning comes from Shalem (2014) in Science.[1]

Unit
Recovery means
Measured by

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Nearby constructs

pooled CRISPR screen1 fields · 1 citationsanchor · a standalone construct perturbation2 fields · 3 citationsjingle · one word, two constructs phenotype4 fields · 4 citationsjingle · one word, four constructs

References

Shalem, O., Sanjana, N. E., Hartenian, E., Shi, X., Scott, D. A., Mikkelsen, T. S., Heckl, D., Ebert, B. L., Root, D. E., Doench, J. G., & Zhang, F. (2014). Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells. Science, 343(6166), 84-87. https://doi.org/10.1126/science.1247005

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