Construct · 1 fields · 1 citations

pooled CRISPR screen: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Functional genomics

testing thousands of gene knockouts at once with a guide library and counting guide abundance after selection.

In functional genomics, pooled CRISPR screen refers to testing thousands of gene knockouts at once with a guide library and counting guide abundance after selection. This meaning comes from Shalem (2014) in Science.[1]

Unit
Recovery means
Measured by

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Nearby constructs

CRISPR screen1 fields · 1 citationsanchor · a standalone construct library1 fields · 1 citationsanchor · a standalone construct selection4 fields · 5 citationsjingle · one word, four constructs

References

Shalem, O., Sanjana, N. E., Hartenian, E., Shi, X., Scott, D. A., Mikkelsen, T. S., Heckl, D., Ebert, B. L., Root, D. E., Doench, J. G., & Zhang, F. (2014). Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells. Science, 343(6166), 84-87. https://doi.org/10.1126/science.1247005

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