Construct · 1 fields · 1 citations

cumulative fraction of response: a standalone construct

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Clinical microbiology

expected share of patients reaching a pharmacodynamic target, found by weighting target attainment by the MIC distribution of a pathogen.

In clinical microbiology, cumulative fraction of response refers to expected share of patients reaching a pharmacodynamic target, found by weighting target attainment by the MIC distribution of a pathogen. This meaning comes from Mouton (2005) in Journal of Antimicrobial Chemotherapy.[1]

Unit
Recovery means
Measured by

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Nearby constructs

probability of target attainment1 fields · 1 citationsanchor · a standalone construct distribution2 fields · 2 citationsjingle · one word, two constructs response4 fields · 4 citationsjingle · one word, four constructs

References

Mouton, J. W., Dudley, M. N., Cars, O., Derendorf, H., & Drusano, G. L. (2005). Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update. Journal of Antimicrobial Chemotherapy, 55(5), 601-607. https://doi.org/10.1093/jac/dki079

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