Construct · 1 fields · 1 citations

CYP2D6 activity score: a standalone construct

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Pharmacology

a number summing the functional value of each CYP2D6 allele a person carries, used to translate genotype into a predicted metabolizer phenotype.

In pharmacology, CYP2D6 activity score refers to a number summing the functional value of each CYP2D6 allele a person carries, used to translate genotype into a predicted metabolizer phenotype. This meaning comes from Gaedigk (2007) in Clinical Pharmacology & Therapeutics.[1]

Unit
Recovery means
Measured by

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Nearby constructs

allele3 fields · 5 citationsjingle · one word, three constructs genotype3 fields · 3 citationsjingle · one word, three constructs metabolizer phenotype1 fields · 1 citationsanchor · a standalone construct

References

Gaedigk, A., Simon, S., Pearce, R., Bradford, L., Kennedy, M., & Leeder, J. (2007). The CYP2D6 Activity Score: Translating Genotype Information into a Qualitative Measure of Phenotype. Clinical Pharmacology & Therapeutics, 83(2), 234-242. https://doi.org/10.1038/sj.clpt.6100406

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