Construct · 1 fields · 1 citations

cytosine base editor: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Genome editing

Cas9 fused to a cytidine deaminase that rewrites a C-G base pair into T-A without a double-strand break.

In genome editing, cytosine base editor refers to cas9 fused to a cytidine deaminase that rewrites a C-G base pair into T-A without a double-strand break. This meaning comes from Komor (2016) in Nature.[1]

Unit
Recovery means
Measured by

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Nearby constructs

base editing1 fields · 1 citationsanchor · a standalone construct base3 fields · 4 citationsjingle · one word, three constructs break2 fields · 4 citationsjingle · one word, two constructs

References

Komor, A. C., Kim, Y. B., Packer, M. S., Zuris, J. A., & Liu, D. R. (2016). Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage. Nature, 533(7603), 420-424. https://doi.org/10.1038/nature17946

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