Construct · 1 fields · 1 citations

DNA methylation: a standalone construct

One name. One construct. A landmark on the map.

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DNAmethylation1 CONSTRUCTDNA methylationHOLLIDAY · MOLECULAR BIOLOGY

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Molecular biology

the addition of methyl groups to DNA bases, proposed as a heritable mechanism for switching genes on and off during development.

In molecular biology, DNA methylation refers to the addition of methyl groups to DNA bases, proposed as a heritable mechanism for switching genes on and off during development. This meaning comes from Holliday (1975) in Science.[1]

Unit
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Measured by

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Nearby constructs

development1 fields · 2 citationsanchor · a standalone constructepigenetic clock1 fields · 1 citationsanchor · a standalone constructepigenetic programming1 fields · 1 citationsanchor · a standalone construct

References

  1. Holliday, R., & Pugh, J. E. (1975). DNA Modification Mechanisms and Gene Activity During Development: Developmental clocks may depend on the enzymic modification of specific bases in repeated DNA sequences. Science, 187(4173), 226-232. https://doi.org/10.1126/science.187.4173.226

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