Construct · 1 fields · 1 citations

dynamic biomarker cascade model: a standalone construct

One name. One construct. A landmark on the map.

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dynamic biomarkercascade model1 CONSTRUCTDynamic biomarkerJACK · NEUROLOGY

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Neurology

a model in which Alzheimer biomarkers become abnormal in a fixed order, from amyloid through tau, atrophy and memory, before and during clinical decline.

In neurology, dynamic biomarker cascade model refers to a model in which Alzheimer biomarkers become abnormal in a fixed order, from amyloid through tau, atrophy and memory, before and during clinical decline. This meaning comes from Jack (2010) in The Lancet Neurology.[1]

Unit
Recovery means
Measured by

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Nearby constructs

cascade4 fields · 4 citationsjingle · one word, four constructsmemory6 fields · 18 citationsjingle · one name, six constructsmodel3 fields · 3 citationsjingle · one word, three constructs

References

  1. Jack, C. R., Knopman, D. S., Jagust, W. J., Shaw, L. M., Aisen, P. S., Weiner, M. W., Petersen, R. C., & Trojanowski, J. Q. (2010). Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. The Lancet Neurology, 9(1), 119-128. https://doi.org/10.1016/s1474-4422(09)70299-6

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