Construct · 1 fields · 1 citations

end-replication problem: a standalone construct

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end-replicationproblem1 CONSTRUCTEnd-replication problemOLOVNIKOV · MOLECULAR BIOLOGY

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Molecular biology

the inability of DNA polymerase to fully copy linear chromosome ends, so they shorten each division, proposed as a limit on cell lifespan.

In molecular biology, end-replication problem refers to the inability of DNA polymerase to fully copy linear chromosome ends, so they shorten each division, proposed as a limit on cell lifespan. This meaning comes from Olovnikov (1973) in Journal of Theoretical Biology.[1]

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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructsdivision4 fields · 7 citationsjingle · one word, four constructslimit3 fields · 3 citationsjingle · one word, three constructs

References

  1. Olovnikov, A. M. (1973). A theory of marginotomy. Journal of Theoretical Biology, 41(1), 181-190. https://doi.org/10.1016/0022-5193(73)90198-7

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