Construct · 1 fields · 1 citations

error catastrophe theory of aging: a standalone construct

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Biology of aging

the theory that errors in the protein-making machinery feed back to produce ever more errors, leading to cellular breakdown with age.

In biology of aging, error catastrophe theory of aging refers to the theory that errors in the protein-making machinery feed back to produce ever more errors, leading to cellular breakdown with age. This meaning comes from Orgel (1963) in Proceedings of the National Academy of Sciences.[1]

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Nearby constructs

aging4 fields · 5 citationsjingle · one word, four constructs breakdown3 fields · 6 citationsjingle · one word, three constructs catastrophe theory1 fields · 1 citationsanchor · a standalone construct

References

Orgel, L. E. (1963). The Maintenance of the Accuracy of Protein Synthesis and Its Relevance to Ageing. Proceedings of the National Academy of Sciences, 49(4), 517-521. https://doi.org/10.1073/pnas.49.4.517

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