Construct · 1 fields · 1 citations

event-driven pharmacology: a standalone construct

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Drug discovery

drug action in which one molecule triggers a lasting event such as target degradation and is recycled, rather than needing sustained target occupancy.

In drug discovery, event-driven pharmacology refers to drug action in which one molecule triggers a lasting event such as target degradation and is recycled, rather than needing sustained target occupancy. This meaning comes from Lai (2016) in Nature Reviews Drug Discovery.[1]

Unit
Recovery means
Measured by

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Nearby constructs

action3 fields · 6 citationsjingle · one word, three constructs degradation3 fields · 5 citationsjingle · one word, three constructs event3 fields · 5 citationsjingle · one word, three constructs

References

Lai, A. C., & Crews, C. M. (2016). Induced protein degradation: an emerging drug discovery paradigm. Nature Reviews Drug Discovery, 16(2), 101-114. https://doi.org/10.1038/nrd.2016.211

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