Construct · 1 fields · 1 citations

gamma-H2AX foci: a standalone construct

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Radiation dosimetry

nuclear foci of histone H2AX phosphorylated at serine 139 that form at DNA double-strand breaks, counted as a marker of radiation damage and dose.

In radiation dosimetry, gamma-H2AX foci refers to nuclear foci of histone H2AX phosphorylated at serine 139 that form at DNA double-strand breaks, counted as a marker of radiation damage and dose. This meaning comes from Rogakou (1998) in Journal of Biological Chemistry.[1]

Unit
Recovery means
Measured by

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Nearby constructs

dose3 fields · 3 citationsinvariant · one construct, three systems form4 fields · 7 citationsjingle · one word, four constructs marker3 fields · 5 citationsjingle · one word, three constructs

References

Rogakou, E. P., Pilch, D. R., Orr, A. H., Ivanova, V. S., & Bonner, W. M. (1998). DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139. Journal of Biological Chemistry, 273(10), 5858-5868. https://doi.org/10.1074/jbc.273.10.5858

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