Construct · 1 fields · 1 citations

genomic storm: a standalone construct

One name. One construct. A landmark on the map.

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genomicstorm1 CONSTRUCTGenomic stormXIAO · CLINICAL IMMUNOLOGY

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Clinical immunology

the rapid, massive and shared change in leukocyte gene expression after severe injury, with simultaneous innate activation and adaptive suppression.

In clinical immunology, genomic storm refers to the rapid, massive and shared change in leukocyte gene expression after severe injury, with simultaneous innate activation and adaptive suppression. This meaning comes from Xiao (2011) in Journal of Experimental Medicine.[1]

Unit
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Nearby constructs

activation4 fields · 4 citationsjingle · one word, four constructsexpression4 fields · 4 citationsjingle · one word, four constructsinjury2 fields · 2 citationsjingle · one word, two carriers

References

  1. Xiao, W., Mindrinos, M. N., Seok, J., Cuschieri, J., Cuenca, A. G., Gao, H., Hayden, D. L., Hennessy, L., Moore, E. E., Minei, J. P., Bankey, P. E., Johnson, J. L., Sperry, J., Nathens, A. B., Billiar, T. R., West, M. A., Brownstein, B. H., Mason, P. H., Baker, H. V., Finnerty, C. C., Jeschke, M. G., López, M. C., Klein, M. B., Gamelli, R. L., Gibran, N. S., Arnoldo, B., Xu, W., Zhang, Y., Calvano, S. E., McDonald-Smith, G. P., Schoenfeld, D. A., Storey, J. D., Cobb, J. P., Warren, H. S., Moldawer, L. L., Herndon, D. N., Lowry, S. F., Maier, R. V., Davis, R. W., & Tompkins, R. G. (2011). A genomic storm in critically injured humans. Journal of Experimental Medicine, 208(13), 2581-2590. https://doi.org/10.1084/jem.20111354

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